Metal Coordination Is Crucial for Geranylgeranyl Diphosphate Synthase–Bisphosphonate Interactions: A Crystallographic and Computational Analysis-Reference-Cited by-同舟云学术

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Metal Coordination Is Crucial for Geranylgeranyl Diphosphate Synthase–Bisphosphonate Interactions: A Crystallographic and Computational Analysis

Published:2019-08-19 Issue:5 Volume:96 Page:580-588
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Lisnyansky Michal,Yariv Elon,Segal Omri,Marom Milit,Loewenstein Anat,Ben-Tal Nir,Giladi Moshe,Haitin Yoni

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference57 articles.

1. PHENIX: a comprehensive Python-based system for macromolecular structure solution

2. The Mevalonate Synthesis Pathway as a Therapeutic Target in Cancer

3. The GTPase superfamily: a conserved switch for diverse cell functions

4. Probing molecular interactions between human carbonic anhydrases (hCAs) and a novel class of benzenesulfonamides;Bruno;J Med Chem,2017

5. A bioinorganic approach to fragment-based drug discovery targeting metalloenzymes;Cohen;Acc Chem Res,2017

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1. Electrospun photocrosslinkable hydrogel fibrous membrane with metal ion trapping capability as an artificial periosteum to promote bone regeneration;Composites Part B: Engineering;2024-02

2. Structural Insight into Geranylgeranyl Diphosphate Synthase (GGDPS) for Cancer Therapy;Molecular Cancer Therapeutics;2023-09-26

3. Geranylgeranyl diphosphate synthase: Role in human health, disease and potential therapeutic target;Clinical and Translational Medicine;2023-01

4. Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use;Bone;2022-03

5. Capturing Magnesium Ions via Microfluidic Hydrogel Microspheres for Promoting Cancellous Bone Regeneration;ACS Nano;2021-08-03

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