IN VITRO METABOLISM OF CHLOROQUINE: IDENTIFICATION OF CYP2C8, CYP3A4, AND CYP2D6 AS THE MAIN ISOFORMS CATALYZING N-DESETHYLCHLOROQUINE FORMATION-Reference-Cited by-同舟云学术

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IN VITRO METABOLISM OF CHLOROQUINE: IDENTIFICATION OF CYP2C8, CYP3A4, AND CYP2D6 AS THE MAIN ISOFORMS CATALYZING N-DESETHYLCHLOROQUINE FORMATION

Published:2003-06 Issue:6 Volume:31 Page:748-754
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Projean Denis,Baune Bruno,Farinotti Robert,Flinois Jean-Pierre,Beaune Philippe,Taburet Anne-Marie,Ducharme Julie

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference43 articles.

1. Chloroquine modulation of specific metabolizing enzymes activities: investigation with selective five drug cocktail

2. Tissue and blood concentrations of chloroquine following chronic administration in the rat

3. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

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