Pharmacokinetic/Pharmacodynamic Modeling of Dexamethasone Anti-Inflammatory and Immunomodulatory Effects in LPS-Challenged Rats: A Model for Cytokine Release Syndrome
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmacology,Molecular Medicine
Reference69 articles.
1. COVID-19 and toll-like receptor 4 (TLR4): SARS-CoV-2 may bind and activate TLR4 to increase ACE2 expression, facilitating entry and causing hyperinflammation;Aboudounya;Mediators Inflamm,2021
2. Dexamethasone exposure in normal‐weight and obese hospitalized COVID ‐19 patients: An observational exploratory trial
3. Dexamethasone, pro‐resolving lipid mediators and resolution of inflammation in COVID‐19
4. Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part II: Sex Differences in Methylprednisolone Pharmacokinetics and Corticosterone Suppression
5. Mechanisms for modulating TNF alpha in immune and inflammatory disease;Baugh;Curr Opin Drug Discov Devel,2001
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