Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390: Implications for the Treatment of Brain Tumors-Reference-Cited by-同舟云学术

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Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390: Implications for the Treatment of Brain Tumors

Published:2022-08-05 Issue:1 Volume:383 Page:91-102
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Talele Surabhi,Zhang Wenjuan,Chen Jiajia,Gupta Shiv K.,Burgenske Danielle M.,Sarkaria Jann N.,Elmquist William F.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference49 articles.

1. Structure and function of the blood–brain barrier

2. Breast Cancer Resistance Protein and P-Glycoprotein in Brain Cancer: Two Gatekeepers Team Up

3. Distribution of Gefitinib to the Brain Is Limited by P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2)-Mediated Active Efflux

4. Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain

5. Testing for the equality of area under the curves when using destructive measurement techniques

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1. Progress of ATM inhibitors: Opportunities and challenges;European Journal of Medicinal Chemistry;2024-11

2. Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization;Science Translational Medicine;2024-02-14

3. Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric Brain Tumors;Journal of Pharmacology and Experimental Therapeutics;2023-10-12

4. How Much is Enough? Impact of Efflux Transporters on Drug delivery Leading to Efficacy in the Treatment of Brain Tumors;Pharmaceutical Research;2023-08-17

5. ATM-Inhibitor AZD1390 Is a Radiosensitizer for Breast Cancer CNS Metastasis;Clinical Cancer Research;2023-08-16

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