Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: “SLC-Phenotyping” Using Primary Human Hepatocytes-Reference-Cited by-同舟云学术

Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: “SLC-Phenotyping” Using Primary Human Hepatocytes

Published:2019-04-11 Issue:1 Volume:370 Page:72-83
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Bi Yi-an,Costales Chester,Mathialagan Sumathy,West Mark,Eatemadpour Soraya,Lazzaro Sarah,Tylaska Laurie,Scialis Renato,Zhang Hui,Umland John,Kimoto Emi^ORCID,Tess David A.,Feng Bo,Tremaine Larry M.,Varma Manthena V. S.^ORCID,Rodrigues A. David

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference54 articles.

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2. Organic Anion Transporter 2 Mediates Hepatic Uptake of Tolbutamide, a CYP2C9 Probe Drug

3. Quantitative assessment of the contribution of sodium-dependent taurocholate co-transporting polypeptide (NTCP) to the hepatic uptake of rosuvastatin, pitavastatin and fluvastatin

4. Reliable rate measurements for active and passive hepatic uptake using plated human hepatocytes;Bi;AAPS J,2017

5. In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

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