Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Epigenetic Regulator Enhancer of Zeste Homolog 2-Reference-Cited by-同舟云学术

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Translational Pharmacokinetic-Pharmacodynamic Modeling for an Orally Available Novel Inhibitor of Epigenetic Regulator Enhancer of Zeste Homolog 2

Published:2020-02-24 Issue:2 Volume:373 Page:220-229
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Yamazaki Shinji,Gukasyan Hovhannes J.,Wang Hui,Uryu Sean,Sharma Shikhar

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference42 articles.

1. Beal S Sheiner L (1992) NONMEM User Guides. NONMEM Project Group, University of California at San Francisco, San Francisco, CA.

2. Pharmacokinetics/pharmacodynamics and the stages of drug development: Role of modeling and simulation

3. Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research

4. Comparison of four basic models of indirect pharmacodynamic responses

5. Polycomb Group Proteins Are Key Regulators of Keratinocyte Function

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