Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding-Reference-Cited by-同舟云学术

Use of a Physiologically Based Pharmacokinetic Model to Study the Time to Reach Brain Equilibrium: An Experimental Analysis of the Role of Blood-Brain Barrier Permeability, Plasma Protein Binding, and Brain Tissue Binding

Published:2005-03-02 Issue:3 Volume:313 Page:1254-1262
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Liu Xingrong,Smith Bill J.,Chen Cuiping,Callegari Ernesto,Becker Stacey L.,Chen Xi,Cianfrogna Julie,Doran Angela C.,Doran Shawn D.,Gibbs John P.,Hosea Natilie,Liu Jianhua,Nelson Frederick R.,Szewc Mark A.,Van Deusen Jeffery

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference35 articles.

1. Treatment of acute ischemic stroke

2. I. Kinetics and metabolism of theobromine in male rats

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