EVALUATION OF THE UTILITY OF BRAIN SLICE METHODS TO STUDY BRAIN PENETRATION
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmaceutical Science,Pharmacology
Reference17 articles.
1. P-Glycoprotein Limits the Brain Penetration of Nonsedating but not Sedating H1-Antagonists
2. The brain slice preparation: a tribute to the pioneer Henry McIlwain
3. Davson H and Segal MB (1995) Physiology of the CSF And Blood-Brain Barriers. CRC Press, Inc., Boca Raton.
4. THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL
5. Fichtl B, Nieciecki AV, and Walter K (1991) Tissue binding versus plasma binding of drugs: general principles and pharmacokinetic consequence, in Advances in Drug Research (Testa B ed), pp 117–166, Academic Press, New York.
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