Rifampin-Mediated Induction of Tamoxifen Metabolism in a Humanized PXR-CAR-CYP3A4/3A7-CYP2D6 Mouse Model-Reference-Cited by-同舟云学术

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Rifampin-Mediated Induction of Tamoxifen Metabolism in a Humanized PXR-CAR-CYP3A4/3A7-CYP2D6 Mouse Model

Published:2016-08-18 Issue:11 Volume:44 Page:1736-1741
ISSN:1521-009X
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metabolism and Disposition

Author:

Chang J. H.,Chen J.,Liu L.,Messick K.,Ly J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference38 articles.

1. Effects of CYP Induction by Rifampicin on Tamoxifen Exposure

2. THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

3. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor

4. Species differences in drug transporters and implications for translating preclinical findings to humans

5. Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity

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2. Comparative Metabolomic Profiling of the Metabolic Differences of Δ9-Tetrahydrocannabinol and Cannabidiol;Molecules;2022-11-04

3. Investigating the Utility of Humanized PXR-CAR-CYP3A4/7 Mouse Model to Assess CYP3A-Mediated Induction;Drug Metabolism and Disposition;2021-04-16

4. Pharmacogenomics of breast cancer: highlighting CYP2D6 and tamoxifen;Journal of Cancer Research and Clinical Oncology;2020-04-08

5. Application of genetically modified rodent models in drug discovery and development for translation of clinical ADME properties;Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters;2020

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