Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus-Associated Hepatocellular Carcinoma-Reference-Cited by-同舟云学术

Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus-Associated Hepatocellular Carcinoma

Published:2016-07-20 Issue:10 Volume:44 Page:1643-1652
ISSN:1521-009X
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metabolism and Disposition

Author:

Tang X.,Ge L.,Chen Z.,Kong S.,Liu W.,Xu Y.,Zeng S.,Chen S.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference27 articles.

1. Expression of P450 and nuclear receptors in normal and end-stage Chinese livers

2. 5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

3. Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes

4. DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter

5. CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype

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