Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily-Reference-Cited by-同舟云学术

Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily

Published:2005-12-08 Issue:3 Volume:316 Page:1300-1309
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Steckelbroeck Stephan,Oyesanmi Busola,Jin Yi,Lee Seon-Hwa,Kloosterboer Helenius J.,Penning Trevor M.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference40 articles.

1. Tibolone: a review

2. Expression Cloning and Characterization of Oxidative 17β- and 3α-Hydroxysteroid Dehydrogenases from Rat and Human Prostate

3. Progestagenic Effects of Tibolone on Human Endometrial Cancer Cells

4. Blom MJ (2001) Steroids and steroid analogues for hormone replacement therapy: metabolism in target tissues. Ph.D. dissertation, University of Utrecht, Utrecht, The Netherlands.

5. Expression and Characterization of Four Recombinant Human Dihydrodiol Dehydrogenase Isoforms: Oxidation of trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene to the Activated o-Quinone Metabolite Benzo[a]pyrene-7,8-dione,

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