Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors

Author:

Maione Sabatino,Bisogno Tiziana,de Novellis Vito,Palazzo Enza,Cristino Luigia,Valenti Marta,Petrosino Stefania,Guglielmotti Vittorio,Rossi Francesco,Marzo Vincenzo Di

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference39 articles.

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2. Bisogno T, Cascio MG, Matias I, De Petrocellis L, Orlando P, Valenti M, and Di Marzo V (2004) Enzymes for 2-AG biosynthesis and metabolism in cell lines and their pharmacological inhibition (Abstract), Meeting of the 2nd International Conference on Phospholipase A2 and 8th International Congress on Platelet-Activating Factor and Related Lipid Mediators; 2004 Oct 6–9; pp 120 Berlin, Germany.

3. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells

4. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

5. Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels

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