In Vivo Responsiveness to Ezetimibe Correlates with Niemann-Pick C1 Like-1 (NPC1L1) Binding Affinity: Comparison of Multiple Species NPC1L1 Orthologs-Reference-Cited by-同舟云学术

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In Vivo Responsiveness to Ezetimibe Correlates with Niemann-Pick C1 Like-1 (NPC1L1) Binding Affinity: Comparison of Multiple Species NPC1L1 Orthologs

Published:2006-09-27 Issue:1 Volume:71 Page:19-29
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Hawes Brian E.,O'Neill Kim A.,Yao Xiaorui,Crona James H.,Davis Harry R.,Graziano Michael P.,Altmann Scott W.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference36 articles.

1. The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption

2. Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol Absorption

3. Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies

4. β-Lactam Cholesterol Absorption Inhibitors

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1. Bioequivalence Study of Ezetimibe Tablets After a Single Oral Dose of 10 mg in Healthy Japanese Subjects Under Fasting Conditions;Clinical Pharmacology in Drug Development;2023-04-06

2. Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption;European Journal of Medicinal Chemistry;2022-02

3. Atherosclerosis: Cholesterol Management;Burger's Medicinal Chemistry and Drug Discovery;2021-04-22

4. A new system to evaluate characteristics of Niemann-Pick C1 Like 1-mediated cholesterol transport using Xenopus laevis oocytes;Biochimica et Biophysica Acta (BBA) - Biomembranes;2021-02

5. Transport via Niemann-Pick C1 Like 1 contributes to the intestinal absorption of ubiquinone;Drug Metabolism and Pharmacokinetics;2020-12

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