The Anthracycline Metabolite Doxorubicinol Abolishes RyR2 Sensitivity to Physiological Changes in Luminal Ca2+ through an Interaction with Calsequestrin-Reference-Cited by-同舟云学术

The Anthracycline Metabolite Doxorubicinol Abolishes RyR2 Sensitivity to Physiological Changes in Luminal Ca2+ through an Interaction with Calsequestrin

Published:2017-09-15 Issue:5 Volume:92 Page:576-587
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Hanna Amy D.,Lam Alexander,Thekkedam Chris,Willemse Hermia,Dulhunty Angela F.,Beard Nicole A.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference50 articles.

1. C-terminal residues of skeletal muscle calsequestrin are essential for calcium binding and for skeletal ryanodine receptor inhibition;Beard;Skelet Muscle,2015

2. Calsequestrin Is an Inhibitor of Skeletal Muscle Ryanodine Receptor Calcium Release Channels

3. Redox modification of ryanodine receptors underlies calcium alternans in a canine model of sudden cardiac death

4. Bound and determined: A computer program for making buffers of defined ion concentrations

5. Investigations of Calsequestrin as a Target for Anthracyclines: Comparison of Functional Effects of Daunorubicin, Daunorubicinol, and Trifluoperazine

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanistic insights into carvedilol's potential protection against doxorubicin-induced cardiotoxicity;European Journal of Pharmaceutical Sciences;2024-09

2. Mandatory role of endoplasmic reticulum and its pentose phosphate shunt in the myocardial defense mechanisms against the redox stress induced by anthracyclines;Molecular and Cellular Biochemistry;2023-12-12

3. The function and regulation of calsequestrin-2: implications in calcium-mediated arrhythmias;Biophysical Reviews;2022-01-07

4. Weighted gene co-expression network-based approach to identify key genes associated with anthracycline-induced cardiotoxicity and construction of miRNA-transcription factor-gene regulatory network;Molecular Medicine;2021-11-03

5. Pharmacokinetics and cardiotoxicity of doxorubicin and its secondary alcohol metabolite in rats;Biomedicine & Pharmacotherapy;2019-08