Prediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent Inhibition-Reference-Cited by-同舟云学术

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Prediction of CYP2D6 Drug Interactions from In Vitro Data: Evidence for Substrate-Dependent Inhibition

Published:2011-10-05 Issue:1 Volume:40 Page:47-53
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

VandenBrink Brooke M.,Foti Robert S.,Rock Dan A.,Wienkers Larry C.,Wahlstrom Jan L.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference44 articles.

1. Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers

2. The antitussive effect of dextromethorphan in relation to CYP2D6 activity

3. Comparative effects of the diastereoisomers, quinine and quinidine in producing phenocopy debrisoquine poor metabolisers (PMs) in healthy volunteers

4. The oxidative metabolism of metoprolol in human liver microsomes: inhibition by the selective serotonin reuptake inhibitors

5. Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine

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