Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate-Reference-Cited by-同舟云学术

Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate

Published:2012-02-10 Issue:5 Volume:40 Page:970-981
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Coughlin John E.,Pandey Rajendra K.,Padmanabhan Seetharamaiyer,O'Loughlin Kathleen G.,Marquis Judith,Green Carol E.,Mirsalis Jon C.,Iyer Radhakrishnan P.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference49 articles.

1. Absorption, tissue distribution and in vivo stability in rats of a hybrid antisense oligonucleotide following oral administration

2. 8-Hydroxyguanosine and 8-methoxyguanosine possess immunostimulating activity for B lymphocytes

3. Pathogen Recognition and Innate Immunity

4. Advances in the Synthesis of Oligonucleotides by the Phosphoramidite Approach

5. Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs

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