Q172H Replacement Overcomes Effects on the Metabolism of Cyclophosphamide and Efavirenz Caused by CYP2B6 Variant with Arg262-Reference-Cited by-同舟云学术

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Q172H Replacement Overcomes Effects on the Metabolism of Cyclophosphamide and Efavirenz Caused by CYP2B6 Variant with Arg262

Published:2011-08-05 Issue:11 Volume:39 Page:2045-2048
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ariyoshi Noritaka,Ohara Miyuki,Kaneko Mayumi,Afuso Sakino,Kumamoto Takuya,Nakamura Hiroyoshi,Ishii Itsuko,Ishikawa Tsutomu,Kitada Mitsukazu

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference23 articles.

1. A Single Nucleotide Polymorphism of CYP2B6 Found in Japanese Enhances Catalytic Activity by Autoactivation

2. Metabolism of Efavirenz and 8-Hydroxyefavirenz by P450 2B6 Leads to Inactivation by Two Distinct Mechanisms

3. Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro

4. Simple Method Based on Fluorescent Detection for the Determination of 4-Hydroxycyclophosphamide in Plasma

5. Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study;Haas;AIDS,2004

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3. Genetic variants, haplotype determination, and function of novel alleles of CYP2B6 in a Han Chinese population;Heliyon;2024-04

4. Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics;Advances in Pharmacological and Pharmaceutical Sciences;2024-01

5. Genetic polymorphisms effect on cyclophosphamide’s tolerability and clinical efficacy in Egyptian patients with lupus nephritis;Pharmacogenetics and Genomics;2023-08-24

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