Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity-Reference-Cited by-同舟云学术

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Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity

Published:2012-02-10 Issue:5 Volume:40 Page:943-951
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Lee Caroline A.,Jones J. P.,Katayama Jonathan,Kaspera Rüdiger,Jiang Ying,Freiwald Sascha,Smith Evan,Walker Gregory S.,Totah Rheem A.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference22 articles.

1. Selective Inhibitors of CYP2J2 Related to Terfenadine Exhibit Strong Activity against Human Cancers in Vitro and in Vivo

2. Cytochrome P450 2J2 Is Highly Expressed in Hematologic Malignant Diseases and Promotes Tumor Cell Growth

3. Identification of Amiodarone Metabolites in Human Bile by Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry

4. Distribution of Soluble Epoxide Hydrolase and of Cytochrome P450 2C8, 2C9, and 2J2 in Human Tissues

5. Variability of CYP2J2 Expression in Human Fetal Tissues

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2. CYP2J2-mediated metabolism of arachidonic acid in heart: A review of its kinetics, inhibition and role in heart rhythm control;Pharmacology & Therapeutics;2024-06

3. Sorafenib reduces the production of epoxyeicosatrienoic acids and leads to cardiac injury by inhibiting CYP2J in rats;Biochemical Pharmacology;2024-05

4. Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes;The AAPS Journal;2024-03-28

5. Investigating the association between CYP2J2 inhibitors and QT prolongation: a literature review;Drug Metabolism Reviews;2024-03-20

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