Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes-Reference-Cited by-同舟云学术

Gemfibrozil Inhibits CYP2C8-Mediated Cerivastatin Metabolism in Human Liver Microsomes

Published:2002-12-01 Issue:12 Volume:30 Page:1352-1356
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Wang Jun-Sheng,Neuvonen Mikko,Wen Xia,Backman Janne T.,Neuvonen Pertti J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference28 articles.

1. Plasma concentrations of active simvastatin acid are increased by gemfibrozil

2. Backman JT, Kyrklund C, Neuvonen M, and Neuvonen PJ (2002) Gemfibrozil greatly increases plasma concentrations of cerivastatin. Clin Pharmacol Ther, in press..

3. Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome P450 isozymes involved.;Boberg;Drug Metab Dispos,1997

4. Biotransformation of cerivastatin in mice, rats and dogs in vivo.;Boberg;Drug Metab Dispos,1998

5. Exercise and diet reduce risk of diabetes, US study shows

Cited by 159 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment;Biomolecules;2024-01-12

2. Fluoroamide-driven intermolecular hydrogen-atom-transfer-enabled intermolecular 1,2-alkylarylation of alkenes;Organic Chemistry Frontiers;2023

3. Effect of Myricetin on CYP2C8 Inhibition to Assess the Likelihood of Drug Interaction Using In Silico, In Vitro, and In Vivo Approaches;ACS Omega;2022-04-04

4. Drug‐Metabolism Enzymes and Transporter Activities as Risk Factors of Selected Marketed Drugs Associated with Drug‐Induced Fatalities;Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity;2021-07-02

5. Nuclear Hormone Receptor Medicinal Chemistry;Burger's Medicinal Chemistry and Drug Discovery;2021-04-26