MicrosomalN-Glucuronidation of Nicotine and Cotinine: Human Hepatic Interindividual, Human Intertissue, and Interspecies Hepatic Variation

Author:

Ghosheh Omar,Hawes Edward M.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference38 articles.

1. Effects of cigarette smoking and carbon monoxide on nicotine and cotinine metabolism

2. Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine.;Benowitz;J Pharmacol Exp Ther,1994

3. Ethnic differences in N-glucuronidation of nicotine and cotinine.;Benowitz;J Pharmacol Exp Ther,1999

4. Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine and trans-3′-hydroxycotinine in smokers.;Byrd;Drug Metab Dispos,1992

5. Characterization of the glucuronide conjugate of cotinine: a previously unidentified major metabolite of nicotine in smokers' urine

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