CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4′-Hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: Structural Basis for Inactivation by RegioselectiveO-Demethylation-Reference-Cited by-同舟云学术

CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4′-Hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: Structural Basis for Inactivation by RegioselectiveO-Demethylation

Published:2002-01-01 Issue:1 Volume:30 Page:74-85
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Uckun Fatih M.,Thoen Jason,Chen Hao,Sudbeck Elise,Mao Chen,Malaviya Ravi,Liu Xing-Ping,Chen Chun-Lin

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

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4. A quantitative HPLC detection method for pharmacokinetic studies of the potent mast cell inhibitor 4-(4′-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline (JANEX-1).;Chen;J Chromatogr B,1999

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