Construction of Humanized<i>CYP1A2</i>Rats Using CRISPR/CRISPR-Associated Protein 9 to Promote Drug Metabolism and Pharmacokinetic Research-Reference-Cited by-同舟云学术

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Construction of HumanizedCYP1A2Rats Using CRISPR/CRISPR-Associated Protein 9 to Promote Drug Metabolism and Pharmacokinetic Research

Published:2023-10-26 Issue:1 Volume:52 Page:56-62
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Liu Jie,Lu Jian,Yao Bingyi,Zhang Yuanjin,Huang Shengbo,Chen Xi,Shen Yifei,Wang Xin^ORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference42 articles.

1. Clozapine pharmacokinetics and pharmacodynamics studied with CYP1A2-null mice

2. Future of ToxicologyMetabolic Activation and Drug Design: Challenges and Opportunities in Chemical Toxicology

3. Differential Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Mice Humanized for CYP1A1 and CYP1A2

4. Dai Z Wu Y Xiong Y Wu J Wang M Sun X Ding X Yang L Sun X Ge G (2023) CYP1A inhibitors: Recent progress, current challenges, and future perspectives. Med Res Rev DOI: 10.1002/med.21982 [published ahead of print].

5. Assessment of Three Human in Vitro Systems in the Generation of Major Human Excretory and Circulating Metabolites

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