In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A<sub>2A</sub>Receptor Antagonist/Inverse Agonist-Reference-Cited by-同舟云学术

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In Vitro Pharmacological Profile of KW-6356, a Novel Adenosine A_2AReceptor Antagonist/Inverse Agonist

Published:2023-03-09 Issue:6 Volume:103 Page:311-324
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Ohno Yutaro,Suzuki Michihiko,Asada Hidetsugu,Kanda Tomoyuki,Saki Mayumi,Miyagi Hikaru,Yasunaga Mai,Suno Chiyo,Iwata So,Saito Jun-ichi,Uchida Shinichi

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference63 articles.

1. Past, present and future of A2A adenosine receptor antagonists in the therapy of Parkinson's disease

2. Some quantitative uses of drug antagonists;Arunlakshana;Br J Pharmacol Chemother,1959

3. Adenosine A2a receptor mRNA is expressed by enkephalin cells but not by somatostatin cells in rat striatum: a co-expression study;Augood;Brain Res Mol Brain Res,1994

4. Parkinson disease

5. Pharmacology and Structure of Isolated Conformations of the Adenosine A2AReceptor Define Ligand Efficacy

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2. Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A_2A Receptor;ACS Pharmacology & Translational Science;2024-04-29

3. Optical Control of Adenosine A_2A Receptor Using Istradefylline Photosensitivity;ACS Chemical Neuroscience;2024-01-26

4. Population Pharmacokinetics of the Novel Adenosine A_2A Antagonist/Inverse Agonist KW‐6356 and Its Active Metabolite Following Single and Multiple Oral Administration in Healthy Individuals and Patients with Parkinson's Disease;Clinical Pharmacology in Drug Development;2024-01-04

5. Randomized controlled trial of KW-6356 monotherapy in patients with early untreated Parkinson's disease;Parkinsonism & Related Disorders;2023-12

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