Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering-Reference-Cited by-同舟云学术

Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering

Published:2014-06-10 Issue:2 Volume:350 Page:412-424
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Mitchell Tracy,Chao Ginger,Sitkoff Doree,Lo Fred,Monshizadegan Hossain,Meyers Daniel,Low Simon,Russo Katie,DiBella Rose,Denhez Fabienne,Gao Mian,Myers Joseph,Duke Gerald,Witmer Mark,Miao Bowman,Ho Siew P.,Khan Javed,Parker Rex A.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference43 articles.

1. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

2. Effects of the Prosegment and pH on the Activity of PCSK9

3. Structural and Biochemical Characterization of the Wild Type PCSK9-EGF(AB) Complex and Natural Familial Hypercholesterolemia Mutants

4. Physiological Parameter Values for Physiologically Based Pharmacokinetic Models

5. Short Communication: Renal Tubular Vacuolation in Animals Treated with Polyethylene-Glycol-Conjugated Proteins

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