Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach-Reference-Cited by-同舟云学术

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Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach

Published:2006-09-08 Issue:12 Volume:34 Page:2083-2090
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Kienhuis Anne S.,Wortelboer Heleen M.,Hoflack Jean-Christophe,Moonen Edwin J.,Kleinjans Jos C.S.,van Ommen Ben,van Delft Joost H. M.,Stierum Rob H.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference44 articles.

1. Beken S, Vanhaecke T, De Smet K, Pauwels M, Vercruysse A, and Rogiers V (2004) Collagengel cultures of rat hepatocytes: collagen-gel sandwich and immobilization cultures, in Cytochrome P450 Protocols (Shephard EA and Phillips IR eds), pp 303–310, Humana Press Inc., Totowa, NJ.

2. Gene Expression in Two Hepatic Cell Lines, Cultured Primary Hepatocytes, and Liver Slices Compared to the in Vivo Liver Gene Expression in Rats: Possible Implications for Toxicogenomics Use of in Vitro Systems

3. Comparative metabolism and kinetics of coumarin in mice and rats

4. Identification of the Cytochromes P450 That Catalyze Coumarin 3,4-Epoxidation and 3-Hydroxylation

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