The Prokinetic Cinitapride Has No Clinically Relevant Pharmacokinetic Interaction and Effect on QT during Coadministration with Ketoconazole-Reference-Cited by-同舟云学术

The Prokinetic Cinitapride Has No Clinically Relevant Pharmacokinetic Interaction and Effect on QT during Coadministration with Ketoconazole

Published:2007-04-16 Issue:7 Volume:35 Page:1149-1156
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Robert Marta,Salvà Miquel,Segarra Rosa,Pavesi Marco,Esbri Ramón,Roberts David,Golor Georg

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference29 articles.

1. Alberti J, Álvarez M, Navarro J and Salvá M (2000) Metabolismo in vitro de cinitaprida en presencia de microsomas hepáticos humanos. Identificación del citocromo P450 responsable del metabolismo de cinitapride. Data on File, Almirall Prodesfarma. S.A., Barcelona.

2. QT-RR relationship in healthy subjects exhibits substantial intersubject variability and high intrasubject stability

3. Recent Topics

4. Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride:in vitrostudies of potential co-medication interactions

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