Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E2 in Liver Fibrosis Is Associated with Reduced Fibrogenesis-Reference-Cited by-同舟云学术

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Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E2 in Liver Fibrosis Is Associated with Reduced Fibrogenesis

Published:2017-09-01 Issue:2 Volume:363 Page:126-135
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Schippers Marlies,Beljaars Leonie,Post Eduard,Lotersztajn Sophie,Reker-Smit Catharina,Han Bing,Munoz-Llancao Pablo,Schmidt Martina,Poelstra Klaas

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference25 articles.

1. Targeting of sugar- and charge-modified albumins to fibrotic rat livers: the accessibility of hepatic cells after chronic bile duct ligation

2. The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue

3. Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat

4. Identification of a Tetrahydroquinoline Analog as a Pharmacological Inhibitor of the cAMP-binding Protein Epac

5. Inducible cyclooxygenase may have anti-inflammatory properties

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1. Targeting cAMP signaling and phosphodiesterase 4 for liver disease treatment;Medicinal Chemistry Research;2024-06-26

2. Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration;The Journal of Pathology;2023-09-21

3. EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model;Journal of Experimental Medicine;2022-04-14

4. Drug Targeting and Nanomedicine: Lessons Learned from Liver Targeting and Opportunities for Drug Innovation;Pharmaceutics;2022-01-17

5. Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection;Parasites & Vectors;2021-05-25

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