GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer's Disease Brain and Improves Cognitive Performance in Preclinical Models

Author:

Medhurst Andrew D.,Atkins Alan R.,Beresford Isabel J.,Brackenborough Kim,Briggs Michael A.,Calver Andrew R.,Cilia Jackie,Cluderay Jane E.,Crook Barry,Davis John B.,Davis Rebecca K.,Davis Robert P.,Dawson Lee A.,Foley Andrew G.,Gartlon Jane,Gonzalez M. Isabel,Heslop Teresa,Hirst Warren D.,Jennings Carol,Jones Declan N. C.,Lacroix Laurent P.,Martyn Abbe,Ociepka Sandrine,Ray Alison,Regan Ciaran M.,Roberts Jennifer C.,Schogger Joanne,Southam Eric,Stean Tania O.,Trail Brenda K.,Upton Neil,Wadsworth Graham,Wald Jeffrey A.,White Trevor,Witherington Jason,Woolley Marie L.,Worby Angela,Wilson David M.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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4. Glaxo Group Limited, assignees. Benzodiazepine derivatives for the treatment of neurological disorders. World patent WO 2004/056369 A1. 2004 Jul 8.

5. Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist

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