The Metabolism and Toxicity of Furosemide in the Wistar Rat and CD-1 Mouse: a Chemical and Biochemical Definition of the Toxicophore-Reference-Cited by-同舟云学术

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The Metabolism and Toxicity of Furosemide in the Wistar Rat and CD-1 Mouse: a Chemical and Biochemical Definition of the Toxicophore

Published:2007-06-07 Issue:3 Volume:322 Page:1208-1220
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Williams Dominic P.,Antoine Daniel J.,Butler Philip J.,Jones Russell,Randle Laura,Payne Anthony,Howard Martin,Gardner Iain,Blagg Julian,Park B. Kevin

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference35 articles.

1. Bioactivation of 4-Ipomeanol by CYP4B1: Adduct Characterization and Evidence for an Enedial Intermediate

2. Elimination of furosemide in healthy subjects and in those with renal failure

3. Pharmacokinetics/pharmacodynamics of furosemide in man: A review

4. Development of an in Vitro Screening Model for the Biosynthesis of Acyl Glucuronide Metabolites and the Assessment of Their Reactivity toward Human Serum Albumin

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1. Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy;DARU Journal of Pharmaceutical Sciences;2024-06-27

2. Comprehensive analysis of a widely pharmaceutical, furosemide, and its degradation products in aquatic systems: Occurrence, fate, and ecotoxicity;Environmental Pollution;2024-05

3. Metabophore-mediated retro-metabolic (‘MeMeReMe’) approach in drug design;Drug Discovery Today;2023-10

4. Tenebrio molitor as a Simple and Cheap Preclinical Pharmacokinetic and Toxicity Model;International Journal of Molecular Sciences;2023-01-24

5. In silico environmental risk assessment of fate and effects of pharmaceuticals and their TPs generated and treated by coupling tertiary processes in hospital wastewater;Environmental Science: Water Research & Technology;2023

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