Inhibition of Geranylgeranyl Diphosphate Synthase Induces Apoptosis through Multiple Mechanisms and Displays Synergy with Inhibition of Other Isoprenoid Biosynthetic Enzymes-Reference-Cited by-同舟云学术

Inhibition of Geranylgeranyl Diphosphate Synthase Induces Apoptosis through Multiple Mechanisms and Displays Synergy with Inhibition of Other Isoprenoid Biosynthetic Enzymes

Published:2007-12-14 Issue:3 Volume:324 Page:1028-1036
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Dudakovic Amel,Wiemer Andrew J.,Lamb Kimberly M.,Vonnahme Laura A.,Dietz Sara E.,Hohl Raymond J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference40 articles.

1. Relative importance of high and low density lipoproteins in the regulation of cholesterol synthesis in the adrenal gland, ovary, and testis of the rat.

2. Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth.

3. The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

4. Front and back by Rho and Rac

5. The farnesyl transferase inhibitor R115777 (Zarnestra®) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa®) and Pamidronate

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structural Insight into Geranylgeranyl Diphosphate Synthase (GGDPS) for Cancer Therapy;Molecular Cancer Therapeutics;2023-09-26

2. In vivo evaluation of combination therapy targeting the isoprenoid biosynthetic pathway;Pharmacological Research;2021-05

3. Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition;Cell Death & Disease;2019-09-30

4. Association between polymorphisms in GGPS1 and RANKL genes and postmenopausal osteoporosis in Romanian women;Balneo Research Journal;2019-09-03

5. The role of cholesterol metabolism in leukemia;Blood Science;2019-08