Measurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion Approach-Reference-Cited by-同舟云学术

Measurement of Michaelis Constants for Cytochrome P450-Mediated Biotransformation Reactions Using a Substrate Depletion Approach

Published:2002-07-01 Issue:7 Volume:30 Page:831-837
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Obach R. Scott,Reed-Hagen Anne E.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference25 articles.

1. Single Dose Kinetics of Thioridazine and Its Two Psychoactive Metabolites in Healthy Humans: A Dose Proportionality Study

2. Expression of human cytochromes P450 in insect cells.;Christopherson;ISSX Proc,1995

3. Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplant.;Chen;Drug Metab Dispos,1997

4. Non-linear pharmacokinetics of MDMA (‘ecstasy’) in humans

5. Phase 1 and pharmacologic study of PN401 and fluorouracil in patients with advanced solid malignancies.;Hidalgo;J Clin Oncol,2000

Cited by 175 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of the Novel, Orally Active, and Selective LPA1 Receptor Antagonist ACT-1016-0707 as a Preclinical Candidate for the Treatment of Fibrotic Diseases;Journal of Medicinal Chemistry;2024-02-13

2. Discovery of a Novel Orally Active, Selective LPA Receptor Type 1 Antagonist, 4-(4-(2-Isopropylphenyl)-4-((2-methoxy-4-methylphenyl)carbamoyl)piperidin-1-yl)-4-oxobutanoic Acid, with a Distinct Molecular Scaffold;Journal of Medicinal Chemistry;2024-02-13

3. Preclinical evaluation of an 18F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2;EJNMMI Radiopharmacy and Chemistry;2024-01-02

4. Metabolism Studies In Vitro and In Vivo;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2024

5. The Potentially Significant Role of CYP3A-Mediated Oxidative Metabolism of Dabigatran Etexilate and Its Intermediate Metabolites in Drug-Drug Interaction Assessments Using Microdose Dabigatran Etexilate;Drug Metabolism and Disposition;2023-05-25