Stimulation of Extracellular Signal-Regulated Kinase Pathway by Suramin with Concomitant Activation of DNA Synthesis in Cultured Cells
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmacology,Molecular Medicine
Reference41 articles.
1. Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors.
2. Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
3. Suramin, an experimental chemotherapeutic drug, activates the receptor for epidermal growth factor and promotes growth of certain malignant cells.
4. MAPK-dependent expression of p21WAFand p27kip1in PMA-induced differentiation of HL60 cells
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