An Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation Study-Reference-Cited by-同舟云学术

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An Assessment of Pharmacokinetics and Antioxidant Activity of Free Silymarin Flavonolignans in Healthy Volunteers: A Dose Escalation Study

Published:2013-07-08 Issue:9 Volume:41 Page:1679-1685
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Zhu Hao-Jie,Brinda Bryan J.,Chavin Kenneth D.,Bernstein Hilary J.,Patrick Kennerly S.,Markowitz John S.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference36 articles.

1. Two Flavonolignans from Milk Thistle (Silybum marianum) Inhibit CYP2C9-Mediated Warfarin Metabolism at Clinically Achievable Concentrations

2. A sensitive LC–MS/MS assay for the simultaneous analysis of the major active components of silymarin in human plasma

3. Absorption and metabolism of milk thistle flavanolignans in humans

4. Oxidative stress, isoprostanes and hepatic fibrosis;Comporti;Histol Histopathol,2009

5. F2-isoprostanes as an indicator and risk factor for coronary heart disease

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