In Vitro Characterization of Axitinib Interactions with Human Efflux and Hepatic Uptake Transporters: Implications for Disposition and Drug Interactions

Author:

Reyner Eric L.,Sevidal Samantha,West Mark A.,Clouser-Roche Andrea,Freiwald Sascha,Fenner Katherine,Ullah Mohammed,Lee Caroline A.,Smith Bill J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference45 articles.

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2. In Vitro Evaluation of Hepatic Transporter-Mediated Clinical Drug-Drug Interactions: Hepatocyte Model Optimization and Retrospective Investigation

3. Meta-analysis of contribution of genetic polymorphisms in drug-metabolizing enzymes or transporters to axitinib pharmacokinetics

4. Tyrosine Kinase Inhibitor Gefitinib Enhances Topotecan Penetration of Gliomas

5. Center for Drug Evaluation and Research (CDER) (2012a) Application Number: 202324Orig1s000, Clinical Pharmacology and Biopharmaceutics Review. http://www.accessdata.fda.gov/drugsatfda_docs/nda/2012/202324Orig1s000ClinPharmR.pdf, U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER).

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