Systemic Exposure, Metabolism, and Elimination of [<sup>14</sup>C]-Labeled Amino Lipid, Lipid 5, after a Single Administration of mRNA Encapsulating Lipid Nanoparticles to Sprague-Dawley Rats-Reference-Cited by-同舟云学术

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Systemic Exposure, Metabolism, and Elimination of [¹⁴C]-Labeled Amino Lipid, Lipid 5, after a Single Administration of mRNA Encapsulating Lipid Nanoparticles to Sprague-Dawley Rats

Published:2023-05-19 Issue:7 Volume:51 Page:804-812
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Burdette Douglas,Ci Lei,Shilliday Barclay,Slauter Richard,Auerbach Andrew,Kenney Matthew,Almarsson Örn,Cheung Eugene,Hendrick Tracy

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference14 articles.

1. Messenger RNA therapy for rare genetic metabolic diseases

2. The emerging role of in vitro-transcribed mRNA in adoptive T cell immunotherapy;Foster;Mol Ther,2019

3. Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes

4. Optimization of Lipid Nanoparticles for Intramuscular Administration of mRNA Vaccines

5. Lipid nanoparticles for mRNA delivery;Hou;Nat Rev Mater,2021

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Opportunities and challenges to implementing mRNA-based vaccines and medicines: lessons from COVID-19;Frontiers in Public Health;2024-08-08

2. Engineering ionizable lipids for rapid biodegradation balances mRNA vaccine efficacy and tolerability;2024-08-03

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