Investigation of Clinical Absorption, Distribution, Metabolism, and Excretion and Pharmacokinetics of the HIV-1 Maturation Inhibitor GSK3640254 Using an Intravenous Microtracer Combined with EnteroTracker for Biliary Sampling-Reference-Cited by-同舟云学术

Investigation of Clinical Absorption, Distribution, Metabolism, and Excretion and Pharmacokinetics of the HIV-1 Maturation Inhibitor GSK3640254 Using an Intravenous Microtracer Combined with EnteroTracker for Biliary Sampling

Published:2022-09-24 Issue:11 Volume:50 Page:1442-1453
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Wen Bo,Zhang Ying,Young Graeme C.,Kenworthy David,Pereira Adrian,Pirhalla Jill,Doyle Janine,Jordon Bethany,Zhan Joyce,Johnson Mark

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference25 articles.

1. Assessment of potential drug interactions by characterization of human drug metabolism pathways using non-invasive bile sampling

2. The importance of the human mass balance study in regulatory submissions;Coppola;CPT Pharmacometrics Syst Pharmacol,2019

3. Apalutamide Absorption, Metabolism, and Excretion in Healthy Men, and Enzyme Reaction in Human Hepatocytes

4. Concomitant oral and intravenous pharmacokinetics of dabrafenib, a BRAF inhibitor, in patients with BRAF V600 mutation-positive solid tumors;Denton;J Clin Pharmacol,2013

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