DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES-Reference-Cited by-同舟云学术

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DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES

Published:2005-03-11 Issue:6 Volume:33 Page:706-713
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Yan Zhengyin,Li Jian,Huebert Norman,Caldwell Gary W.,Du Yanming,Zhong Hua

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference34 articles.

1. Mass spectrometry in the analysis of glutathione conjugates

2. Characterization of a novel diclofenac metabolite in human urine by capillary gas chromatography-negative chemical ionization mass spectrometry

3. Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

4. Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways

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