4-Hydroxylation of Debrisoquine by Human CYP1A1 and Its Inhibition by Quinidine and Quinine-Reference-Cited by-同舟云学术

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4-Hydroxylation of Debrisoquine by Human CYP1A1 and Its Inhibition by Quinidine and Quinine

Published:2002-06-01 Issue:3 Volume:301 Page:1025-1032
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Granvil Camille P.,Krausz Kristopher W.,Gelboin Harry V.,Idle Jeffrey R.,Gonzalez Frank J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference78 articles.

1. Metabolism of debrisoquine sulfate. Identification of some urinary metabolites in rat and man.;Allen;Drug Metab Dispos,1975

2. Comparative effects of the diastereoisomers, quinine and quinidine in producing phenocopy debrisoquine poor metabolisers (PMs) in healthy volunteers.;Ayesh;Chirality,1991

3. Attempts to phenotype human liver samples in vitro for debrisoquine 4-hydroxylase activity.;Boobis;Br J Clin Pharmacol,1985

4. In vivo modulation of CYP enzymes by quinidine and rifampin

5. High-throughput cytochrome P450 inhibition screening via cassette probe-dosing strategy. IV. Validation of a direct injection on-line guard cartridge extraction/tandem mass spectrometry method for simultaneous CYP3A4, 2D6 and 2E1 inhibition assessment

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