Lysosomal Sequestration Determines Intracellular Imatinib Levels-Reference-Cited by-同舟云学术

Lysosomal Sequestration Determines Intracellular Imatinib Levels

Published:2015-06-24 Issue:3 Volume:88 Page:477-487
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Burger Herman,den Dekker Alexander T.,Segeletz Sandra,Boersma Antonius W. M.,de Bruijn Peter,Debiec-Rychter Maria,Taguchi Takahiro,Sleijfer Stefan,Sparreboom Alex,Mathijssen Ron H. J.,Wiemer Erik A. C.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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1. Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy

2. Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy

3. Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

4. Modulation of the Brain Distribution of Imatinib and its Metabolites in Mice by Valspodar, Zosuquidar and Elacridar

5. From in vitro to in vivo: intracellular determination of imatinib and nilotinib may be related with clinical outcome

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