Humanized Thymidine Kinase–NOG Mice Can Be Used to Identify Drugs That Cause Animal-Specific Hepatotoxicity: A Case Study with Furosemide-Reference-Cited by-同舟云学术

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Humanized Thymidine Kinase–NOG Mice Can Be Used to Identify Drugs That Cause Animal-Specific Hepatotoxicity: A Case Study with Furosemide

Published:2015-05-11 Issue:1 Volume:354 Page:73-78
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Xu Dan,Michie Sara A.,Zheng Ming,Takeda Saori,Wu Manhong,Peltz Gary

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference19 articles.

1. Molecular genetic basis for deficient acetaminophen glucuronidation by cats: UGT1A6 is a pseudogene, and evidence for reduced diversity of expressed hepatic UGT1A isoforms

2. The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional

3. Human pharmacogenetic analysis in chimeric mice with ‘humanized livers’

4. Interspecies Differences in Renal Localization of Cyclooxygenase Isoforms: Implications in Nonsteroidal Antiinflammatory Drug-Related Nephrotoxicity

5. Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

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1. Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies;Drug Metabolism and Disposition;2023-07-31

2. Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction;Acta Pharmaceutica Sinica B;2021-12

3. Attenuated P. falciparum Parasite Shows Cytokine Variations in Humanized Mice;Frontiers in Immunology;2020-09-11

4. Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse;Xenobiotica;2020-08-25

5. Advancing Predictive Hepatotoxicity at the Intersection of Experimental, in Silico, and Artificial Intelligence Technologies;Chemical Research in Toxicology;2018-05-03

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