Induction of Cytochrome P450 3A4 in Primary Human Hepatocytes and Activation of the Human Pregnane X Receptor by Tamoxifen and 4-Hydroxytamoxifen-Reference-Cited by-同舟云学术

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Induction of Cytochrome P450 3A4 in Primary Human Hepatocytes and Activation of the Human Pregnane X Receptor by Tamoxifen and 4-Hydroxytamoxifen

Published:2002-05-01 Issue:5 Volume:30 Page:608-612
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Desai Pankaj B.,Nallani Srikanth C.,Sane Rucha S.,Moore Linda B.,Goodwin Bryan J.,Buckley Donna J.,Buckley Arthur R.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference24 articles.

1. Pharmacokinetics of anastrozole and tamoxifen alone and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the ‘Arimidex™ and Tamoxifen Alone or in Combination’ (ATAC) trial

2. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

3. SXR, a novel steroid and xenobioticsensing nuclear receptor

4. Genomic sequencing.

5. Cellular and molecular pharmacology of antiestrogen action and resistance.;Clarke;Pharmacol Rev,2001

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