Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction-Reference-Cited by-同舟云学术

Evaluation of Cynomolgus Monkey Pregnane X Receptor, Primary Hepatocyte, and in Vivo Pharmacokinetic Changes in Predicting Human CYP3A4 Induction

Published:2009-10-15 Issue:1 Volume:38 Page:16-24
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Kim Sean,Dinchuk Joseph E.,Anthony Monique N.,Orcutt Tami,Zoeckler Mary E.,Sauer Mary B.,Mosure Kathleen W.,Vuppugalla Ragini,Grace James E.,Simmermacher Jean,Dulac Heidi A.,Pizzano Jennifer,Sinz Michael

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference26 articles.

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4. Characterization of the Rhesus Monkey CYP3A64 Enzyme: Species Comparisons of CYP3A Substrate Specificity and Kinetics Using Baculovirus-Expressed Recombinant Enzymes

5. Isolation of chimaeric forms of elongation factor EF-Tu by affinity chromatography

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