A Humanized UGT1 Mouse Model Expressing the UGT1A1*28 Allele for Assessing Drug Clearance by UGT1A1-Dependent Glucuronidation

Author:

Cai Hongliang,Nguyen Nghia,Peterkin Vincent,Yang Young-Sun,Hotz Kathy,Beaton La Placa Deirdre,Chen Shujuan,Tukey Robert H.,Stevens Jeffrey C.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

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4. Inherited disorders of bilirubin metabolism;Bosma;J Hepatol,2003

5. Allometric scaling of pharmacokinetic parameters in drug discovery: Can human CL, Vss and t1/2 be predicted fromin-vivo rat data?

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