Pharmacology of PF-4191834, a Novel, Selective Non-Redox 5-Lipoxygenase Inhibitor Effective in Inflammation and Pain-Reference-Cited by-同舟云学术

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Pharmacology of PF-4191834, a Novel, Selective Non-Redox 5-Lipoxygenase Inhibitor Effective in Inflammation and Pain

Published:2010-04-08 Issue:1 Volume:334 Page:294-301
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Masferrer Jaime L.,Zweifel Ben S.,Hardy Medora,Anderson Gary D.,Dufield Dawn,Cortes-Burgos Luz,Pufahl Robert A.,Graneto Matthew

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference37 articles.

1. The 5-lipoxygenase inhibitor zileuton blocks antigen-induced late airway responses, inflammation and airway hyperresponsiveness in allergic sheep

2. Pharmacokinetics and Pharmacodynamics of Zileuton after Oral Administration of Single and Multiple Dose Regimens of Zileuton 600mg in Healthy Volunteers

3. A Randomized Controlled Trial of Intravenous Montelukast in Acute Asthma

4. CJ-13610, an orally active inhibitor of 5-lipoxygenase is efficacious in preclinical models of pain

5. The effect of MK-0591, a novel 5-lipoxygenase activating protein inhibitor, on leukotriene biosynthesis and allergen-induced airway responses in asthmatic subjects in vivo

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