Lansoprazole, a Proton Pump Inhibitor, Mediates Anti-Inflammatory Effect in Gastric Mucosal Cells through the Induction of Heme Oxygenase-1 via Activation of NF-E2-Related Factor 2 and Oxidation of Kelch-Like ECH-Associating Protein 1-Reference-Cited by-同舟云学术

Lansoprazole, a Proton Pump Inhibitor, Mediates Anti-Inflammatory Effect in Gastric Mucosal Cells through the Induction of Heme Oxygenase-1 via Activation of NF-E2-Related Factor 2 and Oxidation of Kelch-Like ECH-Associating Protein 1

Published:2009-07-23 Issue:1 Volume:331 Page:255-264
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Takagi Tomohisa,Naito Yuji,Okada Hitomi,Ishii Takeshi,Mizushima Katsura,Akagiri Satomi,Adachi Satoko,Handa Osamu,Kokura Satoshi,Ichikawa Hiroshi,Itoh Ken,Yamamoto Masayuki,Matsui Hirofumi,Yoshikawa Toshikazu

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference40 articles.

1. Transcriptional Regulation of the Heme Oxygenase-1 Gene Via the Stress Response Element Pathway

2. Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2

3. Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene

4. Beyond gastric acid reduction: Proton pump inhibitors induce heme oxygenase-1 in gastric and endothelial cells

5. Phosphorylation of Nrf2 at Ser40 by Protein Kinase C in Response to Antioxidants Leads to the Release of Nrf2 from INrf2, but Is Not Required for Nrf2 Stabilization/Accumulation in the Nucleus and Transcriptional Activation of Antioxidant Response Element-mediated NAD(P)H:Quinone Oxidoreductase-1 Gene Expression

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