E6201 [(3S,4R,5Z,8S,9S,11E)-14-(Ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a Novel Kinase Inhibitor of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase (MEK)-1 and MEK Kinase-1: In Vitro Characterization of Its Anti-Inflammatory and Antihyperproliferative Activities-Reference-Cited by-同舟云学术

E6201 [(3S,4R,5Z,8S,9S,11E)-14-(Ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a Novel Kinase Inhibitor of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase (MEK)-1 and MEK Kinase-1: In Vitro Characterization of Its Anti-Inflammatory and Antihyperproliferative Activities

Published:2009-08-14 Issue:2 Volume:331 Page:485-495
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Goto Masaki,Chow Jesse,Muramoto Kenzo,Chiba Ken-ichi,Yamamoto Satoshi,Fujita Masanori,Obaishi Hiroshi,Tai Kenji,Mizui Yoshiharu,Tanaka Isao,Young Donna,Yang Hua,Wang Yuan J.,Shirota Hiroshi,Gusovsky Fabian

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference34 articles.

1. Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor

2. Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions

3. Hypothemycin inhibits the proliferative response and modulates the production of cytokines during T cell activation

4. Prevalence of atopic eczema in the community: the Lothian atopic dermatitis study

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