PREDICTION OF IN VITRO INTRINSIC CLEARANCE FROM HEPATOCYTES: COMPARISON OF SUSPENSIONS AND MONOLAYER CULTURES

Author:

Griffin Sarah J.,Houston J. Brian

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference30 articles.

1. Drug Metab Rev 33, 186. (Suppl 1):.

2. HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

3. Carlile DJ (1994) An Assessment of Isolated Hepatocytes as an in Vitro System for Predicting Clearance. Ph.D. thesis, University of Manchester, Manchester, UK.

Cited by 62 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Metabolism Studies In Vitro and In Vivo;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2024

2. In Vitro Methodologies for the Safety Assessment of Drugs;Drugs and a Methodological Compendium;2023

3. Evaluation of Metabolism of a Defined Pesticide Mixture through Multiple In Vitro Liver Models;Toxics;2022-09-27

4. Construction of polysaccharide scaffold-based perfusion bioreactor supporting liver cell aggregates for drug screening;Journal of Biomaterials Science, Polymer Edition;2022-07-26

5. PHYSIOLOGICAL MODELS FOR DRUG METABOLISM AND EXCRETION;Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations;2021-08-18

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3