Development of a Novel Long-Acting Antidiabetic FGF21 Mimetic by Targeted Conjugation to a Scaffold Antibody-Reference-Cited by-同舟云学术

Development of a Novel Long-Acting Antidiabetic FGF21 Mimetic by Targeted Conjugation to a Scaffold Antibody

Published:2013-05-29 Issue:2 Volume:346 Page:270-280
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Huang Jie,Ishino Tetsuya,Chen Gang,Rolzin Paul,Osothprarop Trina F.,Retting Kelsey,Li Lingna,Jin Ping,Matin Marla J.,Huyghe Bernard,Talukdar Saswata,Bradshaw Curt W.,Palanki Moorthy,Violand Bernard N.,Woodnutt Gary,Lappe Rodney W.,Ogilvie Kathleen,Levin Nancy

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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1. Thyroid Hormone Regulates Hepatic Expression of Fibroblast Growth Factor 21 in a PPARα-dependent Manner

2. Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States

3. The FGF family: biology, pathophysiology and therapy

4. Therapeutic Fc-fusion proteins and peptides as successful alternatives to antibodies

5. Fibroblast Growth Factor 21 Controls Glycemia via Regulation of Hepatic Glucose Flux and Insulin Sensitivity

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