Morphine Glucuronidation and Glucosidation Represent Complementary Metabolic Pathways That Are Both Catalyzed by UDP-Glucuronosyltransferase 2B7: Kinetic, Inhibition, and Molecular Modeling Studies-Reference-Cited by-同舟云学术

Morphine Glucuronidation and Glucosidation Represent Complementary Metabolic Pathways That Are Both Catalyzed by UDP-Glucuronosyltransferase 2B7: Kinetic, Inhibition, and Molecular Modeling Studies

Published:2014-01-23 Issue:1 Volume:349 Page:126-137
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Chau Nuy,Elliot David J.,Lewis Benjamin C.,Burns Kushari,Johnston Martin R.,Mackenzie Peter I.,Miners John O.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference55 articles.

1. Mechanism of cadmium-decreased glucuronidation in the rat

2. Direct determination of UDP-glucuronic acid in cell extracts by high-performance liquid chromatography

3. Synthesis of Morphine-3-Glucuronide

4. In vitro-in vivo correlations for drugs eliminated by glucuronidation: Investigations with the model substrate zidovudine

5. S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen

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