Dexamethasone-Mediated Up-Regulation of HumanCYP2A6Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4α to the Proximal Promoter-Reference-Cited by-同舟云学术

Dexamethasone-Mediated Up-Regulation of HumanCYP2A6Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4α to the Proximal Promoter

Published:2007-10-31 Issue:2 Volume:73 Page:451-460
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Onica Tania,Nichols Kathleen,Larin Meghan,Ng Lorraine,Maslen Ann,Dvorak Zdenek,Pascussi Jean-Marc,Vilarem Marie-Josée,Maurel Patrick,Kirby Gordon M.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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1. Interleukin 1? inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance

2. Cortisol increases transfection efficiency of cells

3. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

4. Identification of Constitutive Androstane Receptor and Glucocorticoid Receptor Binding Sites in the CYP2C19 Promoter

5. The Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Cross-Talk with Hepatic Nuclear Factor 4α to Synergistically Activate the HumanCYP2C9Promoter

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